Using Magnesium Supplements: A Syngap Community Discussion

Why write an article about magnesium supplements?

What is magnesium? ‍

  • Magnesium is a mineral, an essential macronutrient that plays important roles in the body, such as supporting muscle and nerve function and energy production. The multiple benefits of magnesium are outlined in articles like this from Healthline, which tells us it “helps regulate neurotransmitters, which send messages throughout your brain and nervous systems.” An important nutrient for sure.
  • Magnesium is obtained mainly by eating a healthy diet with a variety of foods. Some magnesium-rich foods include nuts and seeds, beans and legumes, dairy products, whole grains, and veggies/ leafy greens. (And dark chocolate!) But if diet alone isn’t providing an adequate amount, some look to supplements.
  • There are at least 11 types of magnesium. Different types regulate different bodily systems and reactions. What stood out for me were the first two items listed in the article: synthesizing protein and nerve function. Both of these areas are directly impacted by the SYNGAP1 gene and the SynGAP protein, primary roots of the symptoms in Syngapian children and adults.
  • So, one can see how an adequate amount of magnesium is important for someone with SYNGAP1 and why caregivers are talking about magnesium supplements to help with this.

A note on the laxative properties of magnesium

Highlights of the discussion

What is CALM?

SRF Community Discussion

Some of the discussion that followed:

  • Many parents agreed that magnesium, both CALM and other formulations, has been quite useful in relieving constipation. Some have given up other products in exchange for CALM. The gummies have worked well for some, and the liquid has been recommended by others.
  • There are different CALM products, some for adults and some for kids. Some have melatonin for sleep, others don’t. Always read the labels and suggested dosing per age/population.
  • CALM may or may not be the right magnesium formula for those on a ketogenic diet, as some Syngapians are for seizure control. As with anything on something as specific as keto, please discuss with your healthcare professionals before adding or changing anything.
  • One mom who gives her child ¼ tsp magnesium oxide each morning said it was a “game changer for pooping on the toilet.” (The toilet!)
  • However, another mom found CALM produced foamy looking stools. Eventually it was discovered that her child was magnesium deficient and they began using a liquid ionic magnesium supplement. They have noted good results.
  • Whether the CALM brand is used or another magnesium supplement, the benefits for both sleep and regularity have been experienced by many Syngapians. We hope those in the SRF FaceBook group will continue to share their experiences via the page.

Other over the counter options

Wrap Up



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